Diagnostics - Summary

Drug Delivery - Summary

Diagnostics

            PolyMicrospheres, the leader in microparticle technology, develops and manufactures a complete line of microspheres including five different Plain-Surface microspheres, eight different Carboxyls, SpaceLink microspheres with spacer arms, Lipophilic and Hydrophilic PS and Carboxyl, specialty Carboxyl with steric effects, ready-to-couple and highly-stable Chloromethyl and Epoxy, SupraMag magnetic microparticles, fluorescent/dyed microspheres, Low-Density and High-Density PS and Carboxyl, size/calibration standards, microbeads, and nanospheres  for the early detection of diseases.

Product Summary

• Five different Plain-Surface microspheres

• Eight different Carboxyl microspheres

• Novel Superparamagnetic microparticles with high attraction (highest magnetic loading) and with amino, chloromethyl, and sulfhydryl functional groups for covalent coupling of antibodies or proteins

• Omni-Bind™ Lipophilic Plain-Surface microspheres for better binding of proteins: anionic, zwitterionic and nonionic

• Omni-Bind™ Lipophilic Carboxyl microspheres for better coupling of proteins: anionic, zwitterionic and nonionic

• New and improved SpaceLink™ Carboxyl microspheres: with flexible spacer arms and linker groups already attached for the covalent coupling of ligands.  Improved kinetics of agglutination reactions and reactivity of ligands.

• Highly stable Ready-to-Couple™ Chloromethyl microspheres:   preactivated and ready for easy covalent coupling -- simple coupling chemistry and long shelf life.  Coupling procedure included.

• Highly stable Ready-to-Couple™ Epoxy microspheres: preactivated and ready for fast covalent coupling -- easy coupling method and long shelf life.  Coupling procedure included.

• Hydrophilic Carboxyl microspheres

• Lightly Hydrophilic Polystyrene microspheres

• Specialty Carboxyl with steric effects

• Non-polystyrene Plain-surface microspheres

• Non-polystyrene Carboxyl microspheres

• Fluorescent / dyed Polystyrene microspheres

• Fluorescent / dyed Carboxyl microspheres

• Low-density Plain-surface microspheres

• Low-density Carboxyl microspheres

• High-density microspheres

• Large microbeads

Drug Delivery

Microsphere-based Drug Delivery Systems

            PolyMicrospheres and Advanced Nanotechnologies, Divisions of Vasmo, Inc., are leaders in developing Microparticle and Nanoparticle-based Drug Delivery Systems with embedded chemotherapeutics and other pharmaceutical compounds for the controlled-release delivery of drugs to affected tissues over an extended period.

            PolyMicrospheres, widely recognized for designing and developing microsphere-based drug delivery systems, remains at the forefront of microencapsulation and controlled-release technologies.  Since its founding in 1990, PolyMicrospheres has been dedicated to providing development of novel drug delivery systems to pharmaceutical, medical device, and biotechnology industries.

            Advanced Nanotechnologies is specialized in developing cutting-edge nanoparticle technologies for the new millennium at the molecular level.  Advanced Nanotechnologies is devoted to fostering the development of targeted drug delivery systems. Advanced Nanotech is also focusing on the development of diagnostic devices for the early detection of diseases.

In summary, what we do:

• Design and development of  microsphere-based and nanoparticle-based drug delivery systems and medical and diagnostic devices

  • Wide range of biodegradable and biocompatible matrix materials

  • Variety of particle sizes ranging from 40 nm to 1000 µM

  • Release rates from days to several weeks

• Optimization

• Rapid feasibility studies

• Evaluation and in vitro release studies

• Scale-up and Manufacturing